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Orengedokuto and san'oshashinto improve memory deficits by inhibiting aging-dependent activation of glycogen synthase kinase-3β

BACKGROUND AND AIM: The aging-dependent activation of glycogen synthase kinase-3β (GSK-3β) has been suggested to be important in the onset of dementia. To discover novel therapeutic Kampo medicines for dementia, we examined the effects of orengedokuto (OGT; 黃連解毒湯 huáng lián jiědú tāng) and san'...

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Detalles Bibliográficos
Autores principales:	Fujiwara, Hironori, Yoshida, Jun, Dibwe, Dya Fita, Awale, Suresh, Hoshino, Haruka, Kohama, Hiroshi, Arai, Hiroyuki, Kudo, Yukitsuka, Matsumoto, Kinzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702137/ https://www.ncbi.nlm.nih.gov/pubmed/31453129 http://dx.doi.org/10.1016/j.jtcme.2018.12.001

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