Syringeable immunotherapeutic nanogel reshapes tumor microenvironment and prevents tumor metastasis and recurrence

The low response rate of current cancer immunotherapy suggests the presence of few antigen-specific T cells and a high number of immunosuppressive factors in tumor microenvironment (TME). Here, we develop a syringeable immunomodulatory multidomain nanogel (iGel) that overcomes the limitation by repr...

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Detalles Bibliográficos
Autores principales: Song, Chanyoung, Phuengkham, Hathaichanok, Kim, Young Seob, Dinh, Van Vuong, Lee, Inho, Shin, Il Woo, Shin, Hong Sik, Jin, Seung Mo, Um, Soong Ho, Lee, Hyunseung, Hong, Kwan Soo, Jin, Seon-Mi, Lee, Eunji, Kang, Tae Heung, Park, Yeong-Min, Lim, Yong Taik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702226/
https://www.ncbi.nlm.nih.gov/pubmed/31431623
http://dx.doi.org/10.1038/s41467-019-11730-8

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