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Mesenchyme-free expansion and transplantation of adult alveolar progenitor cells: steps toward cell-based regenerative therapies

Alveolar type-2 (AT2) cells are necessary for the lung’s regenerative response to epithelial insults such as influenza. However, current methods to expand these cells rely on mesenchymal co-culture, complicating the possibility of transplantation following acute injury. Here we developed several mes...

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Detalles Bibliográficos
Autores principales: Weiner, Aaron I., Jackson, Sergio R., Zhao, Gan, Quansah, Kwaku K., Farshchian, Joseph N., Neupauer, Katherine M., Littauer, Elizabeth Q., Paris, Andrew J., Liberti, Derek C., Scott Worthen, G., Morrisey, Edward E., Vaughan, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702233/
https://www.ncbi.nlm.nih.gov/pubmed/31452939
http://dx.doi.org/10.1038/s41536-019-0080-9