Cargando…

A Novel Design of an Intelligent Drug Delivery System Based on Nanoantenna Particles

Compound nanoparticle drug delivery system plays an important role in the interaction with lymph nodes. There are three primary types of lymphocytes: B cells, T cells, and natural killer cells. When the cells of the immune system turn carcinogenic, they assault body cells. The lymph fluid plays an i...

Descripción completa

Detalles Bibliográficos
Autores principales: Abbas, M., Kessentini, A., Loukil, H., Muneer, P., Thafasal Ijyas, V. P., Bushara, S. E., Wase, M. Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702251/
https://www.ncbi.nlm.nih.gov/pubmed/31432280
http://dx.doi.org/10.1186/s11671-019-3102-z
_version_ 1783445187966533632
author Abbas, M.
Kessentini, A.
Loukil, H.
Muneer, P.
Thafasal Ijyas, V. P.
Bushara, S. E.
Wase, M. Abdul
author_facet Abbas, M.
Kessentini, A.
Loukil, H.
Muneer, P.
Thafasal Ijyas, V. P.
Bushara, S. E.
Wase, M. Abdul
author_sort Abbas, M.
collection PubMed
description Compound nanoparticle drug delivery system plays an important role in the interaction with lymph nodes. There are three primary types of lymphocytes: B cells, T cells, and natural killer cells. When the cells of the immune system turn carcinogenic, they assault body cells. The lymph fluid plays an important role in attacking healthy cells of the body; hence, this paper aimed to design a drug delivery system, which can efficiently direct nanoparticles to target the infected cells, helping in high-speed elimination of such cells. The proposed design depends on the interaction between these molecules, and the intelligent nano-controller has the ability to guide the nanoparticles by anaerobic contact. The proposed design proved that the smaller the nanoparticle size and density, the less dynamic viscosity of the liquid would be, which would reflect its resistance to flow. In addition, it was concluded that hydrogen molecules play a significant role in reducing lymphatic fluid resistance due to their low density.
format Online
Article
Text
id pubmed-6702251
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Springer US
record_format MEDLINE/PubMed
spelling pubmed-67022512019-09-02 A Novel Design of an Intelligent Drug Delivery System Based on Nanoantenna Particles Abbas, M. Kessentini, A. Loukil, H. Muneer, P. Thafasal Ijyas, V. P. Bushara, S. E. Wase, M. Abdul Nanoscale Res Lett Nano Express Compound nanoparticle drug delivery system plays an important role in the interaction with lymph nodes. There are three primary types of lymphocytes: B cells, T cells, and natural killer cells. When the cells of the immune system turn carcinogenic, they assault body cells. The lymph fluid plays an important role in attacking healthy cells of the body; hence, this paper aimed to design a drug delivery system, which can efficiently direct nanoparticles to target the infected cells, helping in high-speed elimination of such cells. The proposed design depends on the interaction between these molecules, and the intelligent nano-controller has the ability to guide the nanoparticles by anaerobic contact. The proposed design proved that the smaller the nanoparticle size and density, the less dynamic viscosity of the liquid would be, which would reflect its resistance to flow. In addition, it was concluded that hydrogen molecules play a significant role in reducing lymphatic fluid resistance due to their low density. Springer US 2019-08-20 /pmc/articles/PMC6702251/ /pubmed/31432280 http://dx.doi.org/10.1186/s11671-019-3102-z Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Nano Express
Abbas, M.
Kessentini, A.
Loukil, H.
Muneer, P.
Thafasal Ijyas, V. P.
Bushara, S. E.
Wase, M. Abdul
A Novel Design of an Intelligent Drug Delivery System Based on Nanoantenna Particles
title A Novel Design of an Intelligent Drug Delivery System Based on Nanoantenna Particles
title_full A Novel Design of an Intelligent Drug Delivery System Based on Nanoantenna Particles
title_fullStr A Novel Design of an Intelligent Drug Delivery System Based on Nanoantenna Particles
title_full_unstemmed A Novel Design of an Intelligent Drug Delivery System Based on Nanoantenna Particles
title_short A Novel Design of an Intelligent Drug Delivery System Based on Nanoantenna Particles
title_sort novel design of an intelligent drug delivery system based on nanoantenna particles
topic Nano Express
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702251/
https://www.ncbi.nlm.nih.gov/pubmed/31432280
http://dx.doi.org/10.1186/s11671-019-3102-z
work_keys_str_mv AT abbasm anoveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT kessentinia anoveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT loukilh anoveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT muneerp anoveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT thafasalijyasvp anoveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT busharase anoveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT wasemabdul anoveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT abbasm noveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT kessentinia noveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT loukilh noveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT muneerp noveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT thafasalijyasvp noveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT busharase noveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles
AT wasemabdul noveldesignofanintelligentdrugdeliverysystembasedonnanoantennaparticles