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Secreted Amyloid Precursor Protein-Alpha Promotes Arc Protein Synthesis in Hippocampal Neurons

Secreted amyloid precursor protein-α (sAPPα) is a neuroprotective and memory-enhancing molecule, however, the mechanisms through which sAPPα promotes these effects are not well understood. Recently, we have shown that sAPPα enhances cell-surface expression of glutamate receptors. Activity-related cy...

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Detalles Bibliográficos
Autores principales: Livingstone, Rhys W., Elder, Megan K., Barrett, Maya C., Westlake, Courteney M., Peppercorn, Katie, Tate, Warren P., Abraham, Wickliffe C., Williams, Joanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702288/
https://www.ncbi.nlm.nih.gov/pubmed/31474829
http://dx.doi.org/10.3389/fnmol.2019.00198