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From Clinical Trial Efficacy to Real-Life Effectiveness: Why Conventional Metrics do not Work
BACKGROUND: Randomised, double-blind, clinical trial methodology minimises bias in the measurement of treatment efficacy. However, most phase III trials in non-orphan diseases do not include individuals from the population to whom efficacy findings will be applied in the real world. Thus, a translat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702507/ https://www.ncbi.nlm.nih.gov/pubmed/31359347 http://dx.doi.org/10.1007/s40801-019-0159-z |