Common Molecular Alterations in Canine Oligodendroglioma and Human Malignant Gliomas and Potential Novel Therapeutic Targets

Spontaneous canine (Canis lupus) oligodendroglioma (ODG) holds tremendous potential as an immunocompetent large animal model of human malignant gliomas (MG). However, the feasibility of utilizing this model in pre-clinical studies depends on a thorough understanding of the similarities and differenc...

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Detalles Bibliográficos
Autores principales: Mitchell, Dana, Chintala, Sreenivasulu, Fetcko, Kaleigh, Henriquez, Mario, Tewari, Brij N., Ahmed, Atique, Bentley, R. Timothy, Dey, Mahua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702544/
https://www.ncbi.nlm.nih.gov/pubmed/31475119
http://dx.doi.org/10.3389/fonc.2019.00780

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