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Multifunctional Nanoregulator Reshapes Immune Microenvironment and Enhances Immune Memory for Tumor Immunotherapy

Hypoxia leads to up‐regulation of PD‐L1 and decreases T lymphocyte infiltration, thus boosting immunotherapeutic resistance of tumors. Moreover, tumor‐infiltrating myeloid cells such as myeloid‐derived suppressor cells (MDSCs) correlate with potent immune suppressive activity and resistance to the i...

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Detalles Bibliográficos
Autores principales: Yu, Meng, Duan, Xiaohui, Cai, Yujun, Zhang, Fang, Jiang, Shuqi, Han, Shisong, Shen, Jun, Shuai, Xintao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702652/
https://www.ncbi.nlm.nih.gov/pubmed/31453054
http://dx.doi.org/10.1002/advs.201900037