Septin and Ras regulate cytokinetic abscission in detached cells

BACKGROUND: Integrin-mediated adhesion is normally required for cytokinetic abscission, and failure in the process can generate potentially oncogenic tetraploid cells. Here, detachment-induced formation of oncogenic tetraploid cells was analyzed in non-transformed human BJ fibroblasts and BJ express...

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Detalles Bibliográficos
Autores principales: Gupta, Deepesh Kumar, Kamranvar, Siamak A., Du, Jian, Liu, Liangwen, Johansson, Staffan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702736/
https://www.ncbi.nlm.nih.gov/pubmed/31452675
http://dx.doi.org/10.1186/s13008-019-0051-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702736/
https://www.ncbi.nlm.nih.gov/pubmed/31452675
http://dx.doi.org/10.1186/s13008-019-0051-y

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