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Using the promoters of MerR family proteins as “rheostats” to engineer whole-cell heavy metal biosensors with adjustable sensitivity
BACKGROUND: Whole cell biosensors provide a simple method for the detection of heavy metals. However, previous designs of them rely primarily on simulation of heavy metal resistance systems of bacteria. RESULTS: This study proposes a strategy for the rational design of metal detection circuits based...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702742/ https://www.ncbi.nlm.nih.gov/pubmed/31452678 http://dx.doi.org/10.1186/s13036-019-0202-3 |