Dapagliflozin improves left ventricular remodeling and aorta sympathetic tone in a pig model of heart failure with preserved ejection fraction

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a difficult disease with high morbidity and mortality rates and lacks an effective treatment. Here, we report the therapeutic effect of dapagliflozin, a sodium-glucose cotransporter 2 inhibitor (SGLT2i), on hypertension + hyperlip...

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Detalles Bibliográficos
Autores principales: Zhang, Nannan, Feng, Bin, Ma, Xuexing, Sun, Kangyun, Xu, Guidong, Zhou, Yafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702744/
https://www.ncbi.nlm.nih.gov/pubmed/31429767
http://dx.doi.org/10.1186/s12933-019-0914-1

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