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Different Mechanistic Association of Myopia with Rhegmatogenous Retinal Detachment between Young and Elderly Patients
OBJECTIVES: To investigate the mechanism of rhegmatogenous retinal detachment (RRD) in young and elderly Korean patients based on the results of axial length distribution. SUBJECTS/METHODS: We retrospectively reviewed the medical records of 1599 patients with RRD who had bilateral axial length data...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702806/ https://www.ncbi.nlm.nih.gov/pubmed/31485442 http://dx.doi.org/10.1155/2019/5357241 |
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author | Kim, Min Seok Park, Sang Jun Park, Kyu Hyung Woo, Se Joon |
author_facet | Kim, Min Seok Park, Sang Jun Park, Kyu Hyung Woo, Se Joon |
author_sort | Kim, Min Seok |
collection | PubMed |
description | OBJECTIVES: To investigate the mechanism of rhegmatogenous retinal detachment (RRD) in young and elderly Korean patients based on the results of axial length distribution. SUBJECTS/METHODS: We retrospectively reviewed the medical records of 1599 patients with RRD who had bilateral axial length data examined at one center between 2003 and 2018. Axial lengths were measured using ultrasound or IOLMaster500. The frequency of RRD and axial length distribution according to age groups were investigated. RESULTS: Patients with RRD displayed a bimodal distribution across ages with two age groups showing the highest peak at 55–59 years and a second peak at 25–29 years of age. The mean axial length was significantly longer in patients younger than 50 years old than that in patients ≥ 50 years old (26.18 ± 1.86 mm vs. 24.55 ± 1.67 mm, respectively, p < 0.001). The percentage of patients with high myopia (axial length ≥ 26 mm) in patients < 50 years old was higher than that in those ≥ 50 years old (51.9% vs. 15.0%, respectively, p < 0.001; odds ratio, 6.11; 95% confidence interval, 4.83 to 7.74). CONCLUSIONS: We found a difference in the prevalence of myopia between young and elderly patients with RRD, which corresponds to a bimodal distribution of RRD incidence in East Asian countries. Our data indicate that myopia or high myopia-induced early vitreous detachment appears to be a major mechanism of occurrence of RRD in young East Asian patients, while senile vitreous liquefaction and detachment is the main mechanism of RRD in elderly patients. |
format | Online Article Text |
id | pubmed-6702806 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-67028062019-09-04 Different Mechanistic Association of Myopia with Rhegmatogenous Retinal Detachment between Young and Elderly Patients Kim, Min Seok Park, Sang Jun Park, Kyu Hyung Woo, Se Joon Biomed Res Int Research Article OBJECTIVES: To investigate the mechanism of rhegmatogenous retinal detachment (RRD) in young and elderly Korean patients based on the results of axial length distribution. SUBJECTS/METHODS: We retrospectively reviewed the medical records of 1599 patients with RRD who had bilateral axial length data examined at one center between 2003 and 2018. Axial lengths were measured using ultrasound or IOLMaster500. The frequency of RRD and axial length distribution according to age groups were investigated. RESULTS: Patients with RRD displayed a bimodal distribution across ages with two age groups showing the highest peak at 55–59 years and a second peak at 25–29 years of age. The mean axial length was significantly longer in patients younger than 50 years old than that in patients ≥ 50 years old (26.18 ± 1.86 mm vs. 24.55 ± 1.67 mm, respectively, p < 0.001). The percentage of patients with high myopia (axial length ≥ 26 mm) in patients < 50 years old was higher than that in those ≥ 50 years old (51.9% vs. 15.0%, respectively, p < 0.001; odds ratio, 6.11; 95% confidence interval, 4.83 to 7.74). CONCLUSIONS: We found a difference in the prevalence of myopia between young and elderly patients with RRD, which corresponds to a bimodal distribution of RRD incidence in East Asian countries. Our data indicate that myopia or high myopia-induced early vitreous detachment appears to be a major mechanism of occurrence of RRD in young East Asian patients, while senile vitreous liquefaction and detachment is the main mechanism of RRD in elderly patients. Hindawi 2019-08-07 /pmc/articles/PMC6702806/ /pubmed/31485442 http://dx.doi.org/10.1155/2019/5357241 Text en Copyright © 2019 Min Seok Kim et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Kim, Min Seok Park, Sang Jun Park, Kyu Hyung Woo, Se Joon Different Mechanistic Association of Myopia with Rhegmatogenous Retinal Detachment between Young and Elderly Patients |
title | Different Mechanistic Association of Myopia with Rhegmatogenous Retinal Detachment between Young and Elderly Patients |
title_full | Different Mechanistic Association of Myopia with Rhegmatogenous Retinal Detachment between Young and Elderly Patients |
title_fullStr | Different Mechanistic Association of Myopia with Rhegmatogenous Retinal Detachment between Young and Elderly Patients |
title_full_unstemmed | Different Mechanistic Association of Myopia with Rhegmatogenous Retinal Detachment between Young and Elderly Patients |
title_short | Different Mechanistic Association of Myopia with Rhegmatogenous Retinal Detachment between Young and Elderly Patients |
title_sort | different mechanistic association of myopia with rhegmatogenous retinal detachment between young and elderly patients |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702806/ https://www.ncbi.nlm.nih.gov/pubmed/31485442 http://dx.doi.org/10.1155/2019/5357241 |
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