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Tumor Necrosis Factor-Alpha Antagonist Interferes With the Formation of Granulomatous Multinucleated Giant Cells: New Insights Into Mycobacterium tuberculosis Infection

More than half of tuberculosis cases in the world are due to resuscitation of dormant Mycobacterium tuberculosis (Mtb) sequestered into cell-derived structures called granulomas. It is fairly admitted that cytokines and more particularly Tumor Necrosis Factor (TNF)-α is critical in the control of Mt...

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Detalles Bibliográficos
Autores principales:	Mezouar, Soraya, Diarra, Issa, Roudier, Jean, Desnues, Benoit, Mege, Jean-Louis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702871/ https://www.ncbi.nlm.nih.gov/pubmed/31475008 http://dx.doi.org/10.3389/fimmu.2019.01947

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