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Interferon pathway in SLE: one key to unlocking the mystery of the disease
SLE is characterised by an activation of the interferon (IFN) system, which leads to an increased expression of IFN-regulated genes. The reasons behind the IFN signature in SLE are (1) the existence of endogenous IFN inducers, (2) activation of several IFN-producing cell types, (3) production of man...
Autores principales: | Rönnblom, Lars, Leonard, Dag |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703304/ https://www.ncbi.nlm.nih.gov/pubmed/31497305 http://dx.doi.org/10.1136/lupus-2018-000270 |
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