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The heterogeneous nuclear ribonucleoprotein hnRNPM inhibits RNA virus-triggered innate immunity by antagonizing RNA sensing of RIG-I-like receptors

Recognition of viral RNA by the retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs), including RIG-I and MDA5, initiates innate antiviral responses. Although regulation of RLR-mediated signal transduction has been extensively investigated, how the recognition of viral RNA by RLRs is regulat...

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Detalles Bibliográficos
Autores principales: Cao, Pan, Luo, Wei-Wei, Li, Chen, Tong, Zhen, Zheng, Zhou-Qin, Zhou, Lu, Xiong, Yong, Li, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703689/
https://www.ncbi.nlm.nih.gov/pubmed/31433824
http://dx.doi.org/10.1371/journal.ppat.1007983