Cargando…

The heterogeneous nuclear ribonucleoprotein hnRNPM inhibits RNA virus-triggered innate immunity by antagonizing RNA sensing of RIG-I-like receptors

Recognition of viral RNA by the retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs), including RIG-I and MDA5, initiates innate antiviral responses. Although regulation of RLR-mediated signal transduction has been extensively investigated, how the recognition of viral RNA by RLRs is regulat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Pan, Luo, Wei-Wei, Li, Chen, Tong, Zhen, Zheng, Zhou-Qin, Zhou, Lu, Xiong, Yong, Li, Shu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703689/ https://www.ncbi.nlm.nih.gov/pubmed/31433824 http://dx.doi.org/10.1371/journal.ppat.1007983

Ejemplares similares

The bovine leukemia virus-derived long non-coding RNA AS1-S binds to bovine hnRNPM and alters the interaction between hnRNPM and host mRNAs
por: Andoh, Kiyohiko, et al.
Publicado: (2023)

RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM
por: Ramesh, Nandini, et al.
Publicado: (2020)

Coregulation of alternative splicing by hnRNPM and ESRP1 during EMT
por: Harvey, Samuel E., et al.
Publicado: (2018)

hnRNPM induces translation switch under hypoxia to promote colon cancer development
por: Chen, Tsung-Ming, et al.
Publicado: (2019)

Promoter-Dependent Translation Controlled by p54(nrb) and hnRNPM during Myoblast Differentiation
por: Ainaoui, Nadera, et al.
Publicado: (2015)

Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing
por: Xu, Yilin, et al.
Publicado: (2014)

CDR1as regulated by hnRNPM maintains stemness of periodontal ligament stem cells via miR‐7/KLF4
por: Gu, Xiuge, et al.
Publicado: (2021)

circPTPN12 promotes the progression and sunitinib resistance of renal cancer via hnRNPM/IL-6/STAT3 pathway
por: Shou, Yi, et al.
Publicado: (2023)

hnRNPM guides an alternative splicing program in response to inhibition of the PI3K/AKT/mTOR pathway in Ewing sarcoma cells
por: Passacantilli, Ilaria, et al.
Publicado: (2017)

Discovery of Nuclear DNA-like RNA (dRNA, hnRNA) and Ribonucleoproteins Particles Containing hnRNA
por: Georgiev, G.P.
Publicado: (2016)

Rat liver nuclear skeleton and ribonucleoprotein complexes containing HnRNA
Publicado: (1978)

Reconstitution of nucleoprotein complexes with mammalian heterogeneous nuclear ribonucleoprotein (hnRNP) core proteins
Publicado: (1983)

The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability
por: Chiang, Cindy, et al.
Publicado: (2021)

HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness
por: Ho, Jessica SY, et al.
Publicado: (2021)

The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity
por: Hage, Adam, et al.
Publicado: (2022)

Genomic HIV RNA Induces Innate Immune Responses through RIG-I-Dependent Sensing of Secondary-Structured RNA
por: Berg, Randi K., et al.
Publicado: (2012)

Pan‐cancer analysis of alternative splicing regulator heterogeneous nuclear ribonucleoproteins (hnRNPs) family and their prognostic potential
por: Li, Hao, et al.
Publicado: (2020)

Host Heterogeneous Ribonucleoprotein K (hnRNP K) as a Potential Target to Suppress Hepatitis B Virus Replication
por: Ng, Lisa F. P, et al.
Publicado: (2005)

Impact of Cyclin D1 and Heterogeneous Nuclear Ribonucleoprotein-K (HnRNP-K) on Urinary Bladder Carcinogenesis
por: Aboushousha, Tarek, et al.
Publicado: (2018)

The heterogeneous nuclear ribonucleoprotein (hnRNP) glorund functions in the Drosophila fat body to regulate lipid storage and transport
por: Kolasa, Annabella M., et al.
Publicado: (2021)

RIG-I-like receptors: their regulation and roles in RNA sensing
por: Rehwinkel, Jan, et al.
Publicado: (2020)

C. elegans SUP-46, an HNRNPM family RNA-binding protein that prevents paternally-mediated epigenetic sterility
por: Johnston, Wendy L., et al.
Publicado: (2017)

Heterogeneous Ribonucleoprotein A1 (hnRNPA1) Interacts with the Nucleoprotein of the Influenza a Virus and Impedes Virus Replication
por: Kaur, Ramandeep, et al.
Publicado: (2022)

The Thermodynamic Basis for Viral RNA Detection by the RIG-I Innate Immune Sensor
por: Vela, Adriana, et al.
Publicado: (2012)

Targeting HNRNPM Inhibits Cancer Stemness and Enhances Antitumor Immunity in Wnt-activated Hepatocellular Carcinoma
por: Zhu, Gui-Qi, et al.
Publicado: (2022)

Characterization of RNA driven structural changes in full length RIG-I leading to its agonism or antagonism
por: Sikorska, Justyna, et al.
Publicado: (2023)

Identification of cellular microRNA-136 as a dual regulator of RIG-I-mediated innate immunity that antagonizes H5N1 IAV replication in A549 cells
por: Zhao, Lianzhong, et al.
Publicado: (2015)

Heterogeneous nuclear ribonucleoprotein K (hnRNP K) is a tissue biomarker for detection of early Hepatocellular carcinoma in patients with cirrhosis
por: Guo, Yantong, et al.
Publicado: (2012)

Heterogeneous nuclear ribonucleoprotein (hnRNP) L promotes DNA damage-induced cell apoptosis by enhancing the translation of p53
por: Seo, Ji-Young, et al.
Publicado: (2017)

Heterogeneous nuclear ribonucleoprotein A1 regulates RNA synthesis of a cytoplasmic virus
por: Shi, Stephanie T., et al.
Publicado: (2000)

iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA
por: Luo, Wei-Wei, et al.
Publicado: (2017)

Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I
por: Xu, Jie, et al.
Publicado: (2015)

Novel Pathological Role of hnRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1) in Vascular Smooth Muscle Cell Function and Neointima Hyperplasia
por: Zhang, Li, et al.
Publicado: (2017)

African swine fever virus protein p30 interaction with heterogeneous nuclear ribonucleoprotein K (hnRNP-K) during infection
por: Hernaez, Bruno, et al.
Publicado: (2008)

Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5
por: Hu, Ming-Ming, et al.
Publicado: (2017)

Porcine deltacoronavirus nucleocapsid protein antagonizes IFN-β production by impairing dsRNA and PACT binding to RIG-I
por: Chen, Jun, et al.
Publicado: (2019)

In vitro–transcribed guide RNAs trigger an innate immune response via the RIG-I pathway
por: Wienert, Beeke, et al.
Publicado: (2018)

Centromere Protein (CENP)-W Interacts with Heterogeneous Nuclear Ribonucleoprotein (hnRNP) U and May Contribute to Kinetochore-Microtubule Attachment in Mitotic Cells
por: Chun, Younghwa, et al.
Publicado: (2016)

Heterogenous ribonucleoprotein A18 (hnRNP A18) promotes tumor growth by increasing protein translation of selected transcripts in cancer cells
por: Chang, Elizabeth T., et al.
Publicado: (2016)

Heterogeneous nuclear ribonucleoprotein hnRNPA2/B1 regulates the abundance of the copper-transporter ATP7A in an isoform-dependent manner
por: McCann, Courtney J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ml5fc5vhcr0b2trbqp2a179v52