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Robust Wnt signaling is maintained by a Wg protein gradient and Fz2 receptor activity in the developing Drosophila wing

Wnts are secreted proteins that regulate cell fate during development of all metazoans. Wnt proteins were proposed to spread over several cells to activate signaling directly at a distance. In the Drosophila wing epithelium, an extracellular gradient of the Wnt1 homolog Wingless (Wg) was observed ex...

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Detalles Bibliográficos
Autores principales:	Chaudhary, Varun, Hingole, Swapnil, Frei, Jana, Port, Fillip, Strutt, David, Boutros, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703709/ https://www.ncbi.nlm.nih.gov/pubmed/31399474 http://dx.doi.org/10.1242/dev.174789

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