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Cdc42 defines apical identity and regulates epithelial morphogenesis by promoting apical recruitment of Par6-aPKC and Crumbs

Cdc42 regulates epithelial morphogenesis together with the Par complex (Baz/Par3-Par6-aPKC), Crumbs (Crb/CRB3) and Stardust (Sdt/PALS1). However, how these proteins work together and interact during epithelial morphogenesis is not well understood. To address this issue, we used the genetically amena...

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Detalles Bibliográficos
Autores principales: Nunes de Almeida, Francisca, Walther, Rhian F., Pressé, Mary T., Vlassaks, Evi, Pichaud, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703713/
https://www.ncbi.nlm.nih.gov/pubmed/31405903
http://dx.doi.org/10.1242/dev.175497

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