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Anti-Myelin Proteolipid Protein Peptide Monoclonal Antibodies Recognize Cell Surface Proteins on Developing Neurons and Inhibit Their Differentiation

Using a panel of monoclonal antibodies (mAbs) to myelin proteolipid protein (PLP) peptides, we found that in addition to CNS myelin, mAbs to external face but not cytoplasmic face epitopes immunostained neurons in immature human CNS tissues and in adult hippocampal dentate gyrus and olfactory bulbs,...

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Detalles Bibliográficos
Autores principales: Sobel, Raymond A, Eaton, Mary Jane, Jaju, Prajakta Dilip, Lowry, Eugene, Hinojoza, Julian R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703999/
https://www.ncbi.nlm.nih.gov/pubmed/31400116
http://dx.doi.org/10.1093/jnen/nlz058