Cargando…

Anti-Myelin Proteolipid Protein Peptide Monoclonal Antibodies Recognize Cell Surface Proteins on Developing Neurons and Inhibit Their Differentiation

Using a panel of monoclonal antibodies (mAbs) to myelin proteolipid protein (PLP) peptides, we found that in addition to CNS myelin, mAbs to external face but not cytoplasmic face epitopes immunostained neurons in immature human CNS tissues and in adult hippocampal dentate gyrus and olfactory bulbs,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sobel, Raymond A, Eaton, Mary Jane, Jaju, Prajakta Dilip, Lowry, Eugene, Hinojoza, Julian R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703999/ https://www.ncbi.nlm.nih.gov/pubmed/31400116 http://dx.doi.org/10.1093/jnen/nlz058

Ejemplares similares

Overexpression of the myelin proteolipid protein leads to accumulation of cholesterol and proteolipid protein in endosomes/lysosomes: implications for Pelizaeus-Merzbacher disease
por: Simons, Mikael, et al.
Publicado: (2002)

Analogous amino acid sequences in myelin proteolipid and viral proteins
por: Shaw, Shyh-Yu, et al.
Publicado: (1986)

Human myelin proteolipid protein structure and lipid bilayer stacking
por: Ruskamo, Salla, et al.
Publicado: (2022)

Ethanol down regulates the expression of myelin proteolipid protein in the rat hippocampus
por: Lee, Dong Hoon, et al.
Publicado: (2010)

Assembly of Myelin by Association of Proteolipid Protein with Cholesterol- and Galactosylceramide-Rich Membrane Domains
por: Simons, Mikael, et al.
Publicado: (2000)

A myelin proteolipid protein-LacZ fusion protein is developmentally regulated and targeted to the myelin membrane in transgenic mice
Publicado: (1993)

T cell sensitization to proteolipid protein in myelin basic protein-induced relapsing experimental allergic encephalomyelitis
por: Perry, Linda L., et al.
Publicado: (1991)

The initial events in myelin synthesis: orientation of proteolipid protein in the plasma membrane of cultured oligodendrocytes
Publicado: (1989)

Proteolipid protein–deficient myelin promotes axonal mitochondrial dysfunction via altered metabolic coupling
por: Yin, Xinghua, et al.
Publicado: (2016)

Autoimmune T-Cell Reactivity to Myelin Proteolipids and Glycolipids in Multiple Sclerosis
por: Greer, Judith M.
Publicado: (2013)

Novel B cell-dependent multiple sclerosis model using extracellular domains of myelin proteolipid protein
por: Boyden, Alexander W., et al.
Publicado: (2020)

Autopathogenic T Helper Cell Type 1 (Th1) and Protective Th2 Clones Differ in Their Recognition of the Autoantigenic Peptide of Myelin Proteolipid Protein
por: Das, Mercy Prabhu, et al.
Publicado: (1997)

YY1 negatively regulates mouse myelin proteolipid protein (Plp1) gene expression in oligodendroglial cells
por: Zolova, Olga E, et al.
Publicado: (2011)

Pathogenic myelin-specific antibodies in multiple sclerosis target conformational proteolipid protein 1–anchored membrane domains
por: Owens, Gregory P., et al.
Publicado: (2023)

Azetidine-2-Carboxylic Acid-Induced Oligodendrogliopathy: Relevance to the Pathogenesis of Multiple Sclerosis
por: Sobel, Raymond A, et al.
Publicado: (2022)

Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease
por: Elitt, Matthew S., et al.
Publicado: (2020)

High Frequency of Autoreactive Myelin Proteolipid Protein–Specific T Cells in the Periphery of Naive Mice: Mechanisms of Selection of the Self-Reactive Repertoire
por: Anderson, Ana C., et al.
Publicado: (2000)

Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
Publicado: (1994)

Different proteolipid protein mutants exhibit unique metabolic defects
por: Hüttemann, Maik, et al.
Publicado: (2009)

Role of Proteolipid Protein in HSV-1 Entry in Oligodendrocytic Cells
por: Bello-Morales, Raquel, et al.
Publicado: (2016)

Proteolipid protein 1 gene sequencing of hereditary spastic paraplegia☆
por: Gao, Yu, et al.
Publicado: (2012)

Cathepsin D deficiency delays central nervous system myelination by inhibiting proteolipid protein trafficking from late endosome/lysosome to plasma membrane
por: Guo, Da-Zhi, et al.
Publicado: (2018)

Correlation Between Anti-Myelin Proteolipid Protein (PLP) Antibodies and Disease Severity in Multiple Sclerosis Patients With PLP Response-Permissive HLA Types
por: Greer, Judith M., et al.
Publicado: (2020)

Clinically relevant intronic splicing enhancer mutation in myelin proteolipid protein leads to progressive microglia and astrocyte activation in white and gray matter regions of the brain
por: Bachstetter, Adam D, et al.
Publicado: (2013)

Biomimetic proteolipid vesicles for targeting inflamed tissues
por: Molinaro, R., et al.
Publicado: (2016)

Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis
por: McMahon, Róisín M., et al.
Publicado: (2011)

Disrupted Proteolipid Protein Trafficking Results in Oligodendrocyte Apoptosis in an Animal Model of Pelizaeus-Merzbacher Disease
por: Gow, Alexander, et al.
Publicado: (1998)

Unusual Presentation of Pelizaeus-Merzbacher Disease: Female Patient with Deletion of the Proteolipid Protein 1 Gene
por: Brender, Teva, et al.
Publicado: (2015)

Yeast V-ATPase Proteolipid Ring Acts as a Large-conductance Transmembrane Protein Pore
por: Couoh-Cardel, Sergio, et al.
Publicado: (2016)

Proteolipid Protein 2 Overexpression Indicates Aggressive Tumor Behavior and Adverse Prognosis in Human Gliomas
por: Chen, Yi-Hsuan, et al.
Publicado: (2018)

Reduced expression of proteolipid protein 2 increases ER stress‐induced apoptosis and autophagy in glioblastoma
por: Feng, Zichao, et al.
Publicado: (2019)

Mutation of Proteolipid Protein 1 Gene: From Severe Hypomyelinating Leukodystrophy to Inherited Spastic Paraplegia
por: Khalaf, Guy, et al.
Publicado: (2022)

A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosis
Publicado: (1991)

The Proteolipid Protein Promoter Drives Expression outside of the Oligodendrocyte Lineage during Embryonic and Early Postnatal Development
por: Michalski, John-Paul, et al.
Publicado: (2011)

Plasma Membrane Proteolipid 3 Protein Modulates Amphotericin B Resistance through Sphingolipid Biosynthetic Pathway
por: Bari, Vinay K., et al.
Publicado: (2015)

Epitope-Specific Tolerance Modes Differentially Specify Susceptibility to Proteolipid Protein-Induced Experimental Autoimmune Encephalomyelitis
por: Wang, Lei, et al.
Publicado: (2017)

An intermediate filament-associated protein, p50, recognized by monoclonal antibodies
Publicado: (1983)

Monoclonal antibodies that recognize transcription unit proteins on newt lampbrush chromosomes
Publicado: (1987)

Rare Case of Female with Pelizaeus Mertzbacher Disease due to deletion of Proteolipid Protein 1: A Case Report
por: Kinoshita, Masanosuke, et al.
Publicado: (2018)

The Complex Proteolipidic Behavior of the SARS-CoV-2 Envelope Protein Channel: Weak Selectivity and Heterogeneous Oligomerization
por: Surya, Wahyu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mmcc3385s1lkn81s9hdj3e0hkh