Metastatic urothelial carcinoma to the liver with unknown primary tumor

Cancer of unknown primary (CUP), a rare and aggressive clinical entity, accounts for approximately 3% of all malignancies. CUP with urothelial origin is even more unusual, with no other cases reported in the current literature. As imaging and other studies often do not reveal the tumor origin, the a...

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Autores principales: Cheung, Carling, Zhang, Li, Clifton, Marisa M., Park, Alyssa, Meissner, Matthew, Fulmer, Brant R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704036/
https://www.ncbi.nlm.nih.gov/pubmed/31453109
http://dx.doi.org/10.1016/j.eucr.2019.100993
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author Cheung, Carling
Zhang, Li
Clifton, Marisa M.
Park, Alyssa
Meissner, Matthew
Fulmer, Brant R.
author_facet Cheung, Carling
Zhang, Li
Clifton, Marisa M.
Park, Alyssa
Meissner, Matthew
Fulmer, Brant R.
author_sort Cheung, Carling
collection PubMed
description Cancer of unknown primary (CUP), a rare and aggressive clinical entity, accounts for approximately 3% of all malignancies. CUP with urothelial origin is even more unusual, with no other cases reported in the current literature. As imaging and other studies often do not reveal the tumor origin, the approach to CUP involves a focused search for the primary tumor, relying on guidance from immunohistochemical staining of biopsy specimens. Treatment consists of standard therapies directed at the most likely tumor origin.
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spelling pubmed-67040362019-08-26 Metastatic urothelial carcinoma to the liver with unknown primary tumor Cheung, Carling Zhang, Li Clifton, Marisa M. Park, Alyssa Meissner, Matthew Fulmer, Brant R. Urol Case Rep Oncology Cancer of unknown primary (CUP), a rare and aggressive clinical entity, accounts for approximately 3% of all malignancies. CUP with urothelial origin is even more unusual, with no other cases reported in the current literature. As imaging and other studies often do not reveal the tumor origin, the approach to CUP involves a focused search for the primary tumor, relying on guidance from immunohistochemical staining of biopsy specimens. Treatment consists of standard therapies directed at the most likely tumor origin. Elsevier 2019-08-10 /pmc/articles/PMC6704036/ /pubmed/31453109 http://dx.doi.org/10.1016/j.eucr.2019.100993 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Cheung, Carling
Zhang, Li
Clifton, Marisa M.
Park, Alyssa
Meissner, Matthew
Fulmer, Brant R.
Metastatic urothelial carcinoma to the liver with unknown primary tumor
title Metastatic urothelial carcinoma to the liver with unknown primary tumor
title_full Metastatic urothelial carcinoma to the liver with unknown primary tumor
title_fullStr Metastatic urothelial carcinoma to the liver with unknown primary tumor
title_full_unstemmed Metastatic urothelial carcinoma to the liver with unknown primary tumor
title_short Metastatic urothelial carcinoma to the liver with unknown primary tumor
title_sort metastatic urothelial carcinoma to the liver with unknown primary tumor
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704036/
https://www.ncbi.nlm.nih.gov/pubmed/31453109
http://dx.doi.org/10.1016/j.eucr.2019.100993
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