BTLA suppress acute rejection via regulating TCR downstream signals and cytokines production in kidney transplantation and prolonged allografts survival

Acute rejection is a major risk for renal transplant failure. During this adverse process, activated T cells are considered the main effectors. Recently, B and T lymphocyte attenuator (BTLA), a member of the CD28 family receptor, was reported to be a novel inhibitory regulator of T cell activation i...

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Detalles Bibliográficos
Autores principales: Zhang, Jiayi, Zhang, Hengcheng, Wang, Zijie, Yang, Haiwei, Chen, Hao, Cheng, Hong, Zhou, Jiajun, Zheng, Ming, Tan, Ruoyun, Gu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704067/
https://www.ncbi.nlm.nih.gov/pubmed/31434927
http://dx.doi.org/10.1038/s41598-019-48520-7

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