Systematic gene silencing identified Cryptosporidium nucleoside diphosphate kinase and other molecules as targets for suppression of parasite proliferation in human intestinal cells

Cryptosporidiosis is a major cause of diarrheal disease. The only drug approved for cryptosporidiosis has limited efficacy in high-risk populations. Therefore novel drugs are urgently needed. We have identified several enzymes as potential targets for drug development and we have optimized a rapid m...

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Detalles Bibliográficos
Autores principales: Castellanos-Gonzalez, A., Martinez-Traverso, G., Fishbeck, K., Nava, S., White, A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704102/
https://www.ncbi.nlm.nih.gov/pubmed/31434931
http://dx.doi.org/10.1038/s41598-019-48544-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704102/
https://www.ncbi.nlm.nih.gov/pubmed/31434931
http://dx.doi.org/10.1038/s41598-019-48544-z

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