Cargando…

Divergent engagements between adeno-associated viruses with their cellular receptor AAVR

Adeno-associated virus (AAV) receptor (AAVR) is an essential receptor for the entry of multiple AAV serotypes with divergent rules; however, the mechanism remains unclear. Here, we determine the structures of the AAV1-AAVR and AAV5-AAVR complexes, revealing the molecular details by which PKD1 recogn...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ran, Xu, Guangxue, Cao, Lin, Sun, Zixian, He, Yong, Cui, Mengtian, Sun, Yuna, Li, Shentao, Li, Huapeng, Qin, Lan, Hu, Mingxu, Yuan, Zhengjia, Rao, Zipei, Ding, Wei, Rao, Zihe, Lou, Zhiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704107/ https://www.ncbi.nlm.nih.gov/pubmed/31434885 http://dx.doi.org/10.1038/s41467-019-11668-x

Ejemplares similares

Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR
por: Meyer, Nancy L, et al.
Publicado: (2019)

AAVR-Displaying Interfaces: Serotype-Independent Adeno-Associated Virus Capture and Local Delivery Systems
por: Kim, Seung-Hyun, et al.
Publicado: (2019)

Cross-Species Permissivity: Structure of a Goat Adeno-Associated Virus and Its Complex with the Human Receptor AAVR
por: Large, Edward E., et al.
Publicado: (2022)

Current progress in antiviral strategies
por: Lou, Zhiyong, et al.
Publicado: (2014)

Structural basis for the neurotropic AAV9 and the engineered AAVPHP.eB recognition with cellular receptors
por: Xu, Guangxue, et al.
Publicado: (2022)

Enhanced sensitivity of neutralizing antibody detection for different AAV serotypes using HeLa cells with overexpressed AAVR
por: Zheng, Zhaoyue, et al.
Publicado: (2023)

Architecture of severe fever with thrombocytopenia syndrome virus
por: Sun, Zixian, et al.
Publicado: (2023)

The Structure of an AAV5-AAVR Complex at 2.5 Å Resolution: Implications for Cellular Entry and Immune Neutralization of AAV Gene Therapy Vectors
por: Silveria, Mark A., et al.
Publicado: (2020)

Adeno-associated virus capsid assembly is divergent and stochastic
por: Wörner, Tobias P., et al.
Publicado: (2021)

Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71
por: Dang, Minghao, et al.
Publicado: (2014)

Cyclophilin A Associates with Enterovirus-71 Virus Capsid and Plays an Essential Role in Viral Infection as an Uncoating Regulator
por: Qing, Jie, et al.
Publicado: (2014)

Molecular architecture of the ErbB2 extracellular domain homodimer
por: Hu, Shi, et al.
Publicado: (2015)

Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization
por: He, Yong, et al.
Publicado: (2021)

A Generic Method for Fast and Sensitive Detection of Adeno-Associated Viruses Using Modified AAV Receptor Recombinant Proteins
por: Cui, Mengtian, et al.
Publicado: (2019)

Structures of the N- and C-terminal domains of MHV-A59 nucleocapsid protein corroborate a conserved RNA-protein binding mechanism in coronavirus
por: Ma, Yanlin, et al.
Publicado: (2010)

Structural View and Substrate Specificity of Papain-like Protease from Avian Infectious Bronchitis Virus
por: Kong, Lingying, et al.
Publicado: (2015)

Molecular basis for the inhibition of β-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors
por: Dong, Yu, et al.
Publicado: (2015)

Studies on Inhibition of Proliferation of Enterovirus-71 by Compound YZ-LY-0
por: Yang, Qingzhan, et al.
Publicado: (2015)

Expansion and Functional Divergence of the SHORT VEGETATIVE PHASE (SVP) Genes in Eudicots
por: Liu, Xing, et al.
Publicado: (2018)

The newly emerged SARS-Like coronavirus HCoV-EMC also has an “Achilles’ heel”: current effective inhibitor targeting a 3C-like protease
por: Ren, Zhilin, et al.
Publicado: (2013)

Adeno-Viren
por: Falke, Dietrich
Publicado: (2009)

Crystal Structure of Severe Acute Respiratory Syndrome Coronavirus Spike Protein Fusion Core
por: Xu, Yanhui, et al.
Publicado: (2004)

Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion
por: Yan, Liming, et al.
Publicado: (2015)

Complement Activation by Adeno-Associated Virus-Neutralizing Antibody Complexes
por: West, Cara, et al.
Publicado: (2023)

Identification of serotonin 2A receptor as a novel HCV entry factor by a chemical biology strategy
por: Cao, Lin, et al.
Publicado: (2018)

Structural insights into G domain dimerization and pathogenic mutation of OPA1
por: Yu, Caiting, et al.
Publicado: (2020)

Purification, crystallization and preliminary X-ray analysis of nonstructural protein 2 (nsp2) from avian infectious bronchitis virus
por: Yu, Kun, et al.
Publicado: (2012)

Adeno-associated virus receptor complexes and implications for adeno-associated virus immune neutralization
por: Large, Edward E., et al.
Publicado: (2023)

Structure basis for allosteric regulation of lymphocytic choriomeningitis virus polymerase function by Z matrix protein
por: Liu, Lu, et al.
Publicado: (2023)

Divergent Abiotic Stressors Drive Grassland Community Assembly of Tibet and Mongolia Plateau
por: Wang, Jianming, et al.
Publicado: (2022)

Structural Basis for Coronavirus-mediated Membrane Fusion: CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE
por: Xu, Yanhui, et al.
Publicado: (2004)

A comprehensive procedure for antiviral inhibitor discovery using EV71 as an example
por: Cao, Lin, et al.
Publicado: (2015)

Erratum to: A comprehensive procedure for antiviral inhibitor discovery using EV71 as an example
por: Cao, Lin, et al.
Publicado: (2016)

Syndecan-4 Mediates the Cellular Entry of Adeno-Associated Virus 9
por: Hudák, Anett, et al.
Publicado: (2023)

Structural characterization of Mumps virus fusion protein core
por: Liu, Yueyong, et al.
Publicado: (2006)

Insight into the Ebola virus nucleocapsid assembly mechanism: crystal structure of Ebola virus nucleoprotein core domain at 1.8 Å resolution
por: Dong, Shishang, et al.
Publicado: (2015)

Construct design, biophysical, and biochemical characterization of the fusion core from mouse hepatitis virus (a coronavirus) spike protein
por: Xu, Yanhui, et al.
Publicado: (2004)

Ultrasound Targeted Microbubble Destruction Stimulates Cellular Endocytosis in Facilitation of Adeno-Associated Virus Delivery
por: Jin, Li-Fang, et al.
Publicado: (2013)

IN VITRO TRANSFORMATION BY THE ADENOVIRUS-SV40 HYBRID VIRUSES : II. CHARACTERISTICS OF THE TRANSFORMATION OF HAMSTER CELLS BY THE ADENO 2-, ADENO 3-, AND ADENO 12-SV40 VIRUSES
por: Black, Paul H., et al.
Publicado: (1967)

Structures of human mitofusin 1 provide insight into mitochondrial tethering
por: Qi, Yuanbo, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_slm09o7bi50oqllhonu3nfltdt