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Repeated semen exposure decreases cervicovaginal SIVmac251 infection in rhesus macaques

Semen is the vehicle for virion dissemination in the female reproductive tract (FRT) in male-to-female HIV transmission. Recent data suggests that higher frequency semen exposure is associated with activation of anti-HIV mechanisms in HIV negative sex workers. Here, we use a non-human primate (NHP)...

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Detalles Bibliográficos
Autores principales: Abdulhaqq, Shaheed A., Martinez, Melween, Kang, Guobin, Rodriguez, Idia V., Nichols, Stephanie M., Beaumont, David, Joseph, Jocelin, Azzoni, Livio, Yin, Xiangfan, Wise, Megan, Weiner, David, Liu, Qin, Foulkes, Andrea, Münch, Jan, Kirchhoff, Frank, Coutifaris, Christos, Tomaras, Georgia D., Sariol, Carlos, Marx, Preston A., Li, Qingsheng, Kraiselburd, Edmundo N., Montaner, Luis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704120/
https://www.ncbi.nlm.nih.gov/pubmed/31434895
http://dx.doi.org/10.1038/s41467-019-11814-5