Cargando…

Astragaloside IV Protects Ethanol-Induced Gastric Mucosal Injury by Preventing Mitochondrial Oxidative Stress and the Activation of Mitochondrial Pathway Apoptosis in Rats

Alcohol consumption affects gastric mucosa by multiple and complex mechanisms depending either by direct contact of ethanol or by indirect biological damage induced by its metabolite acetaldehyde. The present study aims at further investigating the mechanism of ethanol-induced gastric mucosa injury...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qin, Shumin, Yin, Jinjin, Huang, Shaogang, Lin, Jingyu, Fang, Zhigang, Zhou, Yunsong, Huang, Keer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704233/ https://www.ncbi.nlm.nih.gov/pubmed/31474858 http://dx.doi.org/10.3389/fphar.2019.00894

Ejemplares similares

Review on the protective mechanism of astragaloside IV against cardiovascular diseases
por: Yang, Chunkun, et al.
Publicado: (2023)

Astragaloside IV, as a potential anticancer agent
por: Xia, Dongqin, et al.
Publicado: (2023)

Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats
por: Su, Jun, et al.
Publicado: (2021)

Astragaloside IV Derivative (LS-102) Alleviated Myocardial Ischemia Reperfusion Injury by Inhibiting Drp1(Ser616) Phosphorylation-Mediated Mitochondrial Fission
por: Chen, Li, et al.
Publicado: (2020)

Protective Effect and Possible Mechanisms of Astragaloside IV in Animal Models of Diabetic Nephropathy: A Preclinical Systematic Review and Meta-Analysis
por: Wang, Hong, et al.
Publicado: (2020)

Astragaloside IV alleviates 1-deoxysphinganine-induced mitochondrial dysfunction during the progression of chronic kidney disease through p62-Nrf2 antioxidant pathway
por: Gui, Ting, et al.
Publicado: (2023)

Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy
por: Luo, Li-Fei, et al.
Publicado: (2021)

Identification of Hub Genes in Protective Effect of Astragaloside IV on Aconitine-Induced Cardiac Damage in Zebrafish Based on Bioinformatics Analysis
por: Wang, Mingzhu, et al.
Publicado: (2020)

Suppressing NK Cells by Astragaloside IV Protects Against Acute Ischemic Stroke in Mice Via Inhibiting STAT3
por: Li, Shichun, et al.
Publicado: (2022)

Astragaloside IV ameliorates diabetic nephropathy by modulating the mitochondrial quality control network
por: Liu, Xinhui, et al.
Publicado: (2017)

A Single, Acute Astragaloside IV Therapy Protects Cardiomyocyte Through Attenuating Superoxide Anion-Mediated Accumulation of Autophagosomes in Myocardial Ischemia-Reperfusion Injury
por: Huang, Kai-yu, et al.
Publicado: (2021)

Rutaecarpine Ameliorates Ethanol-Induced Gastric Mucosal Injury in Mice by Modulating Genes Related to Inflammation, Oxidative Stress and Apoptosis
por: Ren, Sichen, et al.
Publicado: (2020)

A Mechanistic Exploratory Study on the Therapeutic Efficacy of Astragaloside IV Against Diabetic Retinopathy Revealed by Network Pharmacology
por: Zhao, Zhi-Hao, et al.
Publicado: (2022)

Astragaloside IV Attenuated 3,4-Benzopyrene-Induced Abdominal Aortic Aneurysm by Ameliorating Macrophage-Mediated Inflammation
por: Wang, Jiaoni, et al.
Publicado: (2018)

Calcium Sensing Receptor-Related Pathway Contributes to Cardiac Injury and the Mechanism of Astragaloside IV on Cardioprotection
por: Lu, Meili, et al.
Publicado: (2018)

Astragaloside IV Improves Bleomycin-Induced Pulmonary Fibrosis in Rats by Attenuating Extracellular Matrix Deposition
por: Li, Liu-Cheng, et al.
Publicado: (2017)

Therapeutic Potential of Astragaloside IV Against Adriamycin-Induced Renal Damage in Rats via Ferroptosis
por: Qin, Lu-Yun, et al.
Publicado: (2022)

Astragaloside IV Alleviates Infarction Induced Cardiomyocyte Injury by Improving Mitochondrial Morphology and Function
por: Zhang, Wen, et al.
Publicado: (2022)

Elucidation of the binding mechanism of astragaloside IV derivative with human serum albumin and its cardiotoxicity in zebrafish embryos
por: Wu, You-Jiao, et al.
Publicado: (2022)

Astragaloside IV improves the pharmacokinetics of febuxostat in rats with hyperuricemic nephropathy by regulating urea metabolism in gut microbiota
por: Zhao, Zhen Xiong, et al.
Publicado: (2022)

Protective effect of Astragaloside IV on chronic intermittent hypoxia-induced vascular endothelial dysfunction through the calpain-1/SIRT1/AMPK signaling pathway
por: Zhao, Fang, et al.
Publicado: (2022)

Astragaloside IV protects against apoptosis in human degenerative chondrocytes through autophagy activation
por: Liu, Jianhong, et al.
Publicado: (2017)

Astragaloside IV Exerts Cardioprotection in Animal Models of Viral Myocarditis: A Preclinical Systematic Review and Meta-Analysis
por: Zhuang, Zhuang, et al.
Publicado: (2019)

Neuroprotective Effect of Astragaloside IV on Cerebral Ischemia/Reperfusion Injury Rats Through Sirt1/Mapt Pathway
por: Shi, Yi-Hua, et al.
Publicado: (2021)

The Mechanism Actions of Astragaloside IV Prevents the Progression of Hypertensive Heart Disease Based on Network Pharmacology and Experimental Pharmacology
por: Jing, Haoran, et al.
Publicado: (2021)

Astragaloside IV attenuates ferroptosis after subarachnoid hemorrhage via Nrf2/HO-1 signaling pathway
por: Liu, Zhuanghua, et al.
Publicado: (2022)

Astragaloside IV Attenuates Podocyte Apoptosis Mediated by Endoplasmic Reticulum Stress through Upregulating Sarco/Endoplasmic Reticulum Ca(2+)-ATPase 2 Expression in Diabetic Nephropathy
por: Guo, Hengjiang, et al.
Publicado: (2016)

Astragaloside IV ameliorates fat metabolism in the liver of ageing mice through targeting mitochondrial activity
por: Luo, Zhixiao, et al.
Publicado: (2021)

Protective Effects of Astragaloside IV against Amyloid Beta1-42 Neurotoxicity by Inhibiting the Mitochondrial Permeability Transition Pore Opening
por: Sun, Qinru, et al.
Publicado: (2014)

Protective effect of standardised fruit extract of Garcinia cowa Roxb. ex Choisy against ethanol induced gastric mucosal lesions in Wistar rats
por: Gupta, Prakash Chandra, et al.
Publicado: (2021)

Astragaloside IV Alleviates Tacrolimus-Induced Chronic Nephrotoxicity via p62-Keap1-Nrf2 Pathway
por: Gao, Ping, et al.
Publicado: (2021)

Astragaloside IV Relieves Atherosclerosis and Hepatic Steatosis via MAPK/NF-κB Signaling Pathway in LDLR(−/−) Mice
por: Zhang, Yifan, et al.
Publicado: (2022)

Effect of Astragaloside IV on improving cardiac function in rats with heart failure: a preclinical systematic review and meta-analysis
por: Zhang, Zhiyuan, et al.
Publicado: (2023)

Combining Sodium Butyrate With Cisplatin Increases the Apoptosis of Gastric Cancer In Vivo and In Vitro via the Mitochondrial Apoptosis Pathway
por: Li, Yangbo, et al.
Publicado: (2021)

Protective Effects of Astragaloside IV on db/db Mice with Diabetic Retinopathy
por: Ding, Yuzhi, et al.
Publicado: (2014)

Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3β-β-Catenin Pathway in Peritoneal Dialysis
por: He, Jiaqi, et al.
Publicado: (2022)

Astragaloside IV promotes pharmacological effect of Descurainia sophia seeds on isoproterenol-induced cardiomyopathy in rats by synergistically modulating the myosin motor
por: Liu, Xingkai, et al.
Publicado: (2022)

Mitochondrial Delivery of Phenol Substructure Triggers Mitochondrial Depolarization and Apoptosis of Cancer Cells
por: Gazzano, Elena, et al.
Publicado: (2018)

Protective effect of Astragaloside IV against sepsis-induced acute lung injury in rats
por: Huang, Ruiqin, et al.
Publicado: (2016)

Gastroprotective Effects of Astragaloside IV against Acute Gastric Lesion in Rats
por: Mao, Shuai, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_2q3kck71rn1bna2tjd51bfep1h