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Divalent cations can control a switch-like behavior in heterotypic and homotypic RNA coacervates

Liquid-liquid phase separation (LLPS) of RNA-protein complexes plays a major role in the cellular function of membraneless organelles (MLOs). MLOs are sensitive to changes in cellular conditions, such as fluctuations in cytoplasmic ion concentrations. To investigate the effect of these changes on ML...

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Detalles Bibliográficos
Autores principales: Onuchic, Paulo L., Milin, Anthony N., Alshareedah, Ibraheem, Deniz, Ashok A., Banerjee, Priya R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704260/
https://www.ncbi.nlm.nih.gov/pubmed/31434954
http://dx.doi.org/10.1038/s41598-019-48457-x