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Deregulation of folate pathway gene expression correlates with poor prognosis in acute leukemia

The present study analyzed the mRNA expression levels of genes involved in the transport and metabolism of methotrexate (MTX) (RFC1, ABCC1, ABCB1, GGH, FPGS, ATIC, TS, MTHFR, MTRR, MS and MTHFD1) in patients with acute leukemia (AL). The expression levels of the examined genes were analyzed by rever...

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Detalles Bibliográficos
Autores principales:	Organista-Nava, Jorge, Gómez-Gómez, Yazmín, Del Moral-Hernandez, Oscar, Illades-Aguiar, Berenice, Gómez-Santamaria, Jazmin, Rivera-Ramírez, Ana Bertha, Saavedra-Herrera, Mónica Virginia, Jimenez-López, Marco Antonio, Leyva-Vázquez, Marco Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704278/ https://www.ncbi.nlm.nih.gov/pubmed/31452789 http://dx.doi.org/10.3892/ol.2019.10650

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