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Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells

Cancer stem cells (CSCs) have been implicated in the genesis, progression and recurrence of renal cancer. The sonic hedgehog (Shh) pathway serves a critical role in maintaining the stemness of CSCs. Genistein, a major isoflavone component extracted from soybeans and soy products, has been demonstrat...

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Detalles Bibliográficos
Autores principales: Li, Enlai, Zhang, Tao, Sun, Xianchao, Li, Yuan, Geng, Hao, Yu, Dexin, Zhong, Caiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704282/
https://www.ncbi.nlm.nih.gov/pubmed/31452785
http://dx.doi.org/10.3892/ol.2019.10657