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Bending of DNA duplexes with mutation motifs

Mutations can be induced by environmental factors but also arise spontaneously during DNA replication or due to deamination of methylated cytosines at CpG dinucleotides. Sites where mutations occur with higher frequency than would be expected by chance are termed hotspots while sites that contain mu...

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Detalles Bibliográficos
Autores principales: Růžička, Michal, Souček, Přemysl, Kulhánek, Petr, Radová, Lenka, Fajkusová, Lenka, Réblová, Kamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704406/
https://www.ncbi.nlm.nih.gov/pubmed/31230075
http://dx.doi.org/10.1093/dnares/dsz013