Development of high-throughput genotyping method of all 18 HR HPV based on the MALDI-TOF MS platform and compared with the Roche Cobas 4800 HPV assay using clinical specimens

BACKGROUND: To develop a new 18 high-risk human papillomavirus (HR HPV) detection and genotyping assay, which is important to evaluate the risk degree of HR HPV for causing cancers. METHODS: All 18 HR HPV and β-globin relative DNA fragments were synthesized and cloned to a plasmid pUC57 to obtain th...

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Detalles Bibliográficos
Autores principales: Cai, Xushan, Guan, Qinghua, Huan, Yu, Liu, Ziyu, Qi, Jiehua, Ge, Shichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704492/
https://www.ncbi.nlm.nih.gov/pubmed/31438998
http://dx.doi.org/10.1186/s12885-019-6036-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704492/
https://www.ncbi.nlm.nih.gov/pubmed/31438998
http://dx.doi.org/10.1186/s12885-019-6036-z

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