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Development of high-throughput genotyping method of all 18 HR HPV based on the MALDI-TOF MS platform and compared with the Roche Cobas 4800 HPV assay using clinical specimens

BACKGROUND: To develop a new 18 high-risk human papillomavirus (HR HPV) detection and genotyping assay, which is important to evaluate the risk degree of HR HPV for causing cancers. METHODS: All 18 HR HPV and β-globin relative DNA fragments were synthesized and cloned to a plasmid pUC57 to obtain th...

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Detalles Bibliográficos
Autores principales:	Cai, Xushan, Guan, Qinghua, Huan, Yu, Liu, Ziyu, Qi, Jiehua, Ge, Shichao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704492/ https://www.ncbi.nlm.nih.gov/pubmed/31438998 http://dx.doi.org/10.1186/s12885-019-6036-z

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