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CD33 splice site genotype was not associated with outcomes of patients receiving the anti-CD33 drug conjugate SGN-CD33A
We tested whether a single nucleotide polymorphism (SNP) that affects splicing of CD33 predicted response to treatment in adults with acute myeloid leukemia (AML) who received the novel CD33 antibody-drug conjugate SGN-CD33A. This genotype, for the CD33 splice site SNP rs12459419, was not associated...
Autores principales: | Stanchina, Michele, Pastore, Alessandro, Devlin, Sean, Famulare, Christopher, Stein, Eytan, Taylor, Justin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704571/ https://www.ncbi.nlm.nih.gov/pubmed/31439003 http://dx.doi.org/10.1186/s13045-019-0771-0 |
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