Absence of kelch13 artemisinin resistance markers but strong selection for lumefantrine-tolerance molecular markers following 18 years of artemisinin-based combination therapy use in Mpumalanga Province, South Africa (2001–2018)

BACKGROUND: The ability of Plasmodium falciparum parasites to develop resistance to widely used anti-malarials threatens malaria control and elimination efforts. Regular drug efficacy monitoring is essential for ensuring effective treatment policies. In low transmission settings where therapeutic ef...

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Detalles Bibliográficos
Autores principales: Raman, Jaishree, Kagoro, Frank M., Mabuza, Aaron, Malatje, Gillian, Reid, Anthony, Frean, John, Barnes, Karen I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704579/
https://www.ncbi.nlm.nih.gov/pubmed/31438951
http://dx.doi.org/10.1186/s12936-019-2911-y

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