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Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation through β-catenin accumulation
BACKGROUND: Alcohol abuse and alcoholism lead to alcohol liver disease such as alcoholic fatty liver. Parkin is a component of the multiprotein E3 ubiquitin ligase complex and is associated with hepatic lipid accumulation. However, the role of parkin in ethanol-induced liver disease has not been rep...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704582/ https://www.ncbi.nlm.nih.gov/pubmed/31438968 http://dx.doi.org/10.1186/s12964-019-0424-5 |