WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1

BACKGROUND: N6-methyladenosine (m6A) methylation, a well-known modification with new epigenetic functions, has been reported to participate in the tumorigenesis of hepatocellular carcinoma (HCC), providing novel insights into the molecular pathogenesis of this disease. However, as the key component...

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Detalles Bibliográficos
Autores principales: Chen, Yunhao, Peng, Chuanhui, Chen, Junru, Chen, Diyu, Yang, Beng, He, Bin, Hu, Wendi, Zhang, Yanpeng, Liu, Hua, Dai, Longfei, Xie, Haiyang, Zhou, Lin, Wu, Jian, Zheng, Shusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704583/
https://www.ncbi.nlm.nih.gov/pubmed/31438961
http://dx.doi.org/10.1186/s12943-019-1053-8

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