Prediction of regulatory targets of alternative isoforms of the epidermal growth factor receptor in a glioblastoma cell line

BACKGROUND: The epidermal growth factor receptor (EGFR) is a major regulator of proliferation in tumor cells. Elevated expression levels of EGFR are associated with prognosis and clinical outcomes of patients in a variety of tumor types. There are at least four splice variants of the mRNA encoding f...

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Detalles Bibliográficos
Autores principales: Weinholdt, Claus, Wichmann, Henri, Kotrba, Johanna, Ardell, David H., Kappler, Matthias, Eckert, Alexander W., Vordermark, Dirk, Grosse, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704634/
https://www.ncbi.nlm.nih.gov/pubmed/31438847
http://dx.doi.org/10.1186/s12859-019-2944-9

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