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Concurrent therapy with immune checkpoint inhibitors and TNFα blockade in patients with gastrointestinal immune-related adverse events
BACKGROUND: Immune checkpoint inhibitors (ICI) have demonstrated remarkable efficacy as cancer therapeutics, however, their use remains limited due to the development of immune related adverse events (irAEs). Immune related enterocolitis (irEC) is among the most common severe irAEs leading to the di...
Autores principales: | Badran, Yousef R., Cohen, Justine V., Brastianos, Priscilla K., Parikh, Aparna R., Hong, Theodore S., Dougan, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704680/ https://www.ncbi.nlm.nih.gov/pubmed/31439050 http://dx.doi.org/10.1186/s40425-019-0711-0 |
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