Discovery and SAR Research for Antivirus Activity of Novel Butenolide on Influenza A Virus H1N1 In Vitro and In Vivo

[Image: see text] Influenza viruses (IV) cause substantial morbidity and mortality through routine seasonal spread and epidemics. A novel series of butenolides were discovered to be able to inhibit influenza H1N1 activity in vitro, and the SAR for anti-influenza activity was investigated. By optimiz...

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Detalles Bibliográficos
Autores principales: Wang, Zhenya, Hu, Xiaoning, Li, Yuanyuan, Mou, Xiaodong, Wang, Congcong, Chen, Xinli, Tan, Yayun, Wu, Chunli, Liu, Hongmin, Xu, Haiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705239/
https://www.ncbi.nlm.nih.gov/pubmed/31460454
http://dx.doi.org/10.1021/acsomega.9b01421

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