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Discovery and SAR Research for Antivirus Activity of Novel Butenolide on Influenza A Virus H1N1 In Vitro and In Vivo
[Image: see text] Influenza viruses (IV) cause substantial morbidity and mortality through routine seasonal spread and epidemics. A novel series of butenolides were discovered to be able to inhibit influenza H1N1 activity in vitro, and the SAR for anti-influenza activity was investigated. By optimiz...
Autores principales: | Wang, Zhenya, Hu, Xiaoning, Li, Yuanyuan, Mou, Xiaodong, Wang, Congcong, Chen, Xinli, Tan, Yayun, Wu, Chunli, Liu, Hongmin, Xu, Haiwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705239/ https://www.ncbi.nlm.nih.gov/pubmed/31460454 http://dx.doi.org/10.1021/acsomega.9b01421 |
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