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Consenso latinoamericano para definir, categorizar y notificar patógenos multirresistentes, con resistencia extendida o panresistentes

This document presents a Latin American consensus to standardize definitions of different levels of antimicrobial resistance in bacteria of public health importance. Inclusion and exclusion criteria are described for antibiotics to include (availability, relevance, and existence of cut-off values) a...

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Autores principales: Jiménez Pearson, María Antonieta, Galas, Marcelo, Corso, Alejandra, Hormazábal, Juan C., Duarte Valderrama, Carolina, Salgado Marcano, Nuris, Ramón-Pardo, Pilar, Melano, Roberto G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Organización Panamericana de la Salud 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705331/
https://www.ncbi.nlm.nih.gov/pubmed/31456820
http://dx.doi.org/10.26633/RPSP.2019.65
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author Jiménez Pearson, María Antonieta
Galas, Marcelo
Corso, Alejandra
Hormazábal, Juan C.
Duarte Valderrama, Carolina
Salgado Marcano, Nuris
Ramón-Pardo, Pilar
Melano, Roberto G.
author_facet Jiménez Pearson, María Antonieta
Galas, Marcelo
Corso, Alejandra
Hormazábal, Juan C.
Duarte Valderrama, Carolina
Salgado Marcano, Nuris
Ramón-Pardo, Pilar
Melano, Roberto G.
author_sort Jiménez Pearson, María Antonieta
collection PubMed
description This document presents a Latin American consensus to standardize definitions of different levels of antimicrobial resistance in bacteria of public health importance. Inclusion and exclusion criteria are described for antibiotics to include (availability, relevance, and existence of cut-off values) and for methodologies to use. Three gram-negative microorganisms with a great impact in the hospital environment (Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter spp.) were selected as a pilot proposal. The lack of cut-off values for certain antibiotics (e.g., tigecycline, fosfomycin, and colistin), crucial in treating infections caused by multi-drug resistant or extensively drug-resistant pathogens, led to the need to discuss and agree on provisional cut-off values for monitoring resistance to these drugs. The work team also addressed and reached consensus on easier-to-use alternative susceptibility tests, other than methods approved by international guidelines, for routine testing in clinical bacteriology laboratories. The main benefit of this document is to provide Latin American laboratories with a standardized and consensual framework for the identification and constant and unified surveillance of resistant microorganisms. The recommendations included in this document are the result of consensus among representatives of the national reference laboratories in the countries belonging to the Latin American Surveillance Network of Antimicrobial Resistance, coordinated by the Pan American Health Organization.
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spelling pubmed-67053312019-08-27 Consenso latinoamericano para definir, categorizar y notificar patógenos multirresistentes, con resistencia extendida o panresistentes Jiménez Pearson, María Antonieta Galas, Marcelo Corso, Alejandra Hormazábal, Juan C. Duarte Valderrama, Carolina Salgado Marcano, Nuris Ramón-Pardo, Pilar Melano, Roberto G. Rev Panam Salud Publica Informe Especial This document presents a Latin American consensus to standardize definitions of different levels of antimicrobial resistance in bacteria of public health importance. Inclusion and exclusion criteria are described for antibiotics to include (availability, relevance, and existence of cut-off values) and for methodologies to use. Three gram-negative microorganisms with a great impact in the hospital environment (Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter spp.) were selected as a pilot proposal. The lack of cut-off values for certain antibiotics (e.g., tigecycline, fosfomycin, and colistin), crucial in treating infections caused by multi-drug resistant or extensively drug-resistant pathogens, led to the need to discuss and agree on provisional cut-off values for monitoring resistance to these drugs. The work team also addressed and reached consensus on easier-to-use alternative susceptibility tests, other than methods approved by international guidelines, for routine testing in clinical bacteriology laboratories. The main benefit of this document is to provide Latin American laboratories with a standardized and consensual framework for the identification and constant and unified surveillance of resistant microorganisms. The recommendations included in this document are the result of consensus among representatives of the national reference laboratories in the countries belonging to the Latin American Surveillance Network of Antimicrobial Resistance, coordinated by the Pan American Health Organization. Organización Panamericana de la Salud 2019-08-22 /pmc/articles/PMC6705331/ /pubmed/31456820 http://dx.doi.org/10.26633/RPSP.2019.65 Text en https://creativecommons.org/licenses/by/4.0/ Este es un artículo de acceso abierto distribuido bajo los términos de la licencia Creative Commons Attribution-NonCommercial-NoDerivs 3.0 IGO, que permite su uso, distribución y reproducción en cualquier medio, siempre que el trabajo original se cite de la manera adecuada. No se permiten modificaciones a los artículos ni su uso comercial. Al reproducir un artículo no debe haber ningún indicio de que la OPS o el artículo avalan a una organización o un producto específico. El uso del logo de la OPS no está permitido. Esta leyenda debe conservarse, junto con la URL original del artículo.
spellingShingle Informe Especial
Jiménez Pearson, María Antonieta
Galas, Marcelo
Corso, Alejandra
Hormazábal, Juan C.
Duarte Valderrama, Carolina
Salgado Marcano, Nuris
Ramón-Pardo, Pilar
Melano, Roberto G.
Consenso latinoamericano para definir, categorizar y notificar patógenos multirresistentes, con resistencia extendida o panresistentes
title Consenso latinoamericano para definir, categorizar y notificar patógenos multirresistentes, con resistencia extendida o panresistentes
title_full Consenso latinoamericano para definir, categorizar y notificar patógenos multirresistentes, con resistencia extendida o panresistentes
title_fullStr Consenso latinoamericano para definir, categorizar y notificar patógenos multirresistentes, con resistencia extendida o panresistentes
title_full_unstemmed Consenso latinoamericano para definir, categorizar y notificar patógenos multirresistentes, con resistencia extendida o panresistentes
title_short Consenso latinoamericano para definir, categorizar y notificar patógenos multirresistentes, con resistencia extendida o panresistentes
title_sort consenso latinoamericano para definir, categorizar y notificar patógenos multirresistentes, con resistencia extendida o panresistentes
topic Informe Especial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705331/
https://www.ncbi.nlm.nih.gov/pubmed/31456820
http://dx.doi.org/10.26633/RPSP.2019.65
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