Bioceramic cement in the filling of bone defects in rats

PURPOSE: To evaluate PBS(®)MCIMMO cement in the filling of bone defects. METHODS: Thirty-six adult male Wistar rats were divided into three groups of twelve individuals each (group 1, group 2 and group 3). In all groups, a bone failure in the femur was induced, 2.0 mm wide and 7.0 mm deep. In group...

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Detalles Bibliográficos
Autores principales: Zerbinatti, Christiano Cândido, Veiga, Daniela Francescato, Oliveira, Monique Amanda Bastista, Mundim, Fiorita Gonzales Lopes, Pereira, Rodrigo Machado, Azevedo, Francisco, Schnaider, Taylor Brandão, da Silva, José Dias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705333/
https://www.ncbi.nlm.nih.gov/pubmed/31432992
http://dx.doi.org/10.1590/s0102-865020190060000001
Descripción
Sumario:PURPOSE: To evaluate PBS(®)MCIMMO cement in the filling of bone defects. METHODS: Thirty-six adult male Wistar rats were divided into three groups of twelve individuals each (group 1, group 2 and group 3). In all groups, a bone failure in the femur was induced, 2.0 mm wide and 7.0 mm deep. In group 1, the PBS(®)MCIMMO cement was applied to the bone defect produced and a titanium implant (CONNECTION(®)) 1.5 mm thick and 6 mm long was installed. In group 2, only the PBS(®) CIMMO cement was installed. In group 3, only bone failure was performed. Kruskal Wallis tests were performed to compare the mean area among the three groups. RESULTS: In all comparisons, significance was observed for group 2 (p = 0.0014–0.0026). CONCLUSION: The PBS(®)CIMMO cement induced bone neoformation, and integration between the newly formed bone, cement, and implant was observed.

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