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Involvement of TLR4 in the protective effect of intra-articular administration of curcumin on rat experimental osteoarthritis

PURPOSE: In view of the principal role of Toll-like receptor 4 (TLR4) in mediating sterile inflammatory response contributing to osteoarthritis (OA) pathogenesis, we used lipopolysaccharide (LPS), a known TLR4 activator, to clarify whether modulation of TLR4 contributed to the protective actions of...

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Detalles Bibliográficos
Autores principales:	Yan, Dan, He, Bingshu, Guo, Jie, Li, Shulan, Wang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705335/ https://www.ncbi.nlm.nih.gov/pubmed/31432995 http://dx.doi.org/10.1590/s0102-865020190060000004

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