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Comparative study of peritoneal adhesions after intraperitoneal implantation in rats of meshes of polypropylene versus polypropylene/polyglecaprone versus polyester/porcine collagen

PURPOSE: To Compare the extent and intensity of adhesions formed between the intra-abdominal organs and the intraperitoneal implants of polypropylene mesh versus polypropylene/polyglecaprone versus polyester/porcine collagen used for correction of abdominal wall defect in rats. METHODS: After the de...

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Autores principales: Ribeiro, Waston Gonçalves, Rodrigues, Diego Vinnicyus Santos, Atta, Francisco Felipe Moreira, Ramos, Izabelle Smith Frazão, Frazão, Fabiola Nassar Sousa, Torres, Orlando Jorge Martins, Pitombo, Marcos Bettini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705338/
https://www.ncbi.nlm.nih.gov/pubmed/31432994
http://dx.doi.org/10.1590/s0102-865020190060000003
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author Ribeiro, Waston Gonçalves
Rodrigues, Diego Vinnicyus Santos
Atta, Francisco Felipe Moreira
Ramos, Izabelle Smith Frazão
Frazão, Fabiola Nassar Sousa
Torres, Orlando Jorge Martins
Pitombo, Marcos Bettini
author_facet Ribeiro, Waston Gonçalves
Rodrigues, Diego Vinnicyus Santos
Atta, Francisco Felipe Moreira
Ramos, Izabelle Smith Frazão
Frazão, Fabiola Nassar Sousa
Torres, Orlando Jorge Martins
Pitombo, Marcos Bettini
author_sort Ribeiro, Waston Gonçalves
collection PubMed
description PURPOSE: To Compare the extent and intensity of adhesions formed between the intra-abdominal organs and the intraperitoneal implants of polypropylene mesh versus polypropylene/polyglecaprone versus polyester/porcine collagen used for correction of abdominal wall defect in rats. METHODS: After the defect in the abdominal wall, thirty Wistar rats were placed in three groups (ten animals each) for intraperitoneal mesh implant: polypropylene group, polypropylene/polyglecaprone group, and polyester/porcine collagen group. The macroscopic evaluation of the extent and intensity of adhesions was performed 21 days after the implant. RESULTS: The polypropylene group had a higher statistically significant impairment due to visceral adhesions (p value = 0.002) and a higher degree of intense adherence in relation to polypropylene/polyglecaprone and polyester/porcine collagen groups (p value<0.001). The polyester/porcine collagen group showed more intense adhesions than the polypropylene/polyglecaprone group (p value=0.035). CONCLUSIONS: The intraperitoneal implantation of polypropylene meshes to correct defects of the abdominal wall caused the appearance of extensive and firm adhesions to intra-abdominal structures. The use of polypropylene/polyglecaprone or polyester/porcine collagen tissue-separating meshes reduces the number and degree of adhesions formed.
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spelling pubmed-67053382019-08-29 Comparative study of peritoneal adhesions after intraperitoneal implantation in rats of meshes of polypropylene versus polypropylene/polyglecaprone versus polyester/porcine collagen Ribeiro, Waston Gonçalves Rodrigues, Diego Vinnicyus Santos Atta, Francisco Felipe Moreira Ramos, Izabelle Smith Frazão Frazão, Fabiola Nassar Sousa Torres, Orlando Jorge Martins Pitombo, Marcos Bettini Acta Cir Bras Original Articles PURPOSE: To Compare the extent and intensity of adhesions formed between the intra-abdominal organs and the intraperitoneal implants of polypropylene mesh versus polypropylene/polyglecaprone versus polyester/porcine collagen used for correction of abdominal wall defect in rats. METHODS: After the defect in the abdominal wall, thirty Wistar rats were placed in three groups (ten animals each) for intraperitoneal mesh implant: polypropylene group, polypropylene/polyglecaprone group, and polyester/porcine collagen group. The macroscopic evaluation of the extent and intensity of adhesions was performed 21 days after the implant. RESULTS: The polypropylene group had a higher statistically significant impairment due to visceral adhesions (p value = 0.002) and a higher degree of intense adherence in relation to polypropylene/polyglecaprone and polyester/porcine collagen groups (p value<0.001). The polyester/porcine collagen group showed more intense adhesions than the polypropylene/polyglecaprone group (p value=0.035). CONCLUSIONS: The intraperitoneal implantation of polypropylene meshes to correct defects of the abdominal wall caused the appearance of extensive and firm adhesions to intra-abdominal structures. The use of polypropylene/polyglecaprone or polyester/porcine collagen tissue-separating meshes reduces the number and degree of adhesions formed. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2019-08-19 /pmc/articles/PMC6705338/ /pubmed/31432994 http://dx.doi.org/10.1590/s0102-865020190060000003 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Ribeiro, Waston Gonçalves
Rodrigues, Diego Vinnicyus Santos
Atta, Francisco Felipe Moreira
Ramos, Izabelle Smith Frazão
Frazão, Fabiola Nassar Sousa
Torres, Orlando Jorge Martins
Pitombo, Marcos Bettini
Comparative study of peritoneal adhesions after intraperitoneal implantation in rats of meshes of polypropylene versus polypropylene/polyglecaprone versus polyester/porcine collagen
title Comparative study of peritoneal adhesions after intraperitoneal implantation in rats of meshes of polypropylene versus polypropylene/polyglecaprone versus polyester/porcine collagen
title_full Comparative study of peritoneal adhesions after intraperitoneal implantation in rats of meshes of polypropylene versus polypropylene/polyglecaprone versus polyester/porcine collagen
title_fullStr Comparative study of peritoneal adhesions after intraperitoneal implantation in rats of meshes of polypropylene versus polypropylene/polyglecaprone versus polyester/porcine collagen
title_full_unstemmed Comparative study of peritoneal adhesions after intraperitoneal implantation in rats of meshes of polypropylene versus polypropylene/polyglecaprone versus polyester/porcine collagen
title_short Comparative study of peritoneal adhesions after intraperitoneal implantation in rats of meshes of polypropylene versus polypropylene/polyglecaprone versus polyester/porcine collagen
title_sort comparative study of peritoneal adhesions after intraperitoneal implantation in rats of meshes of polypropylene versus polypropylene/polyglecaprone versus polyester/porcine collagen
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705338/
https://www.ncbi.nlm.nih.gov/pubmed/31432994
http://dx.doi.org/10.1590/s0102-865020190060000003
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