Lesion activity and chronic demyelination are the major determinants of brain atrophy in MS

OBJECTIVE: To evaluate the combined effect of lesion activity and pathologic processes occurring in both chronically demyelinated lesions and normal-appearing white matter (NAWM) on brain atrophy in MS. METHODS: Pre- and post-gadolinium T1, fluid attenuation inversion recovery, and diffusion tensor...

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Detalles Bibliográficos
Autores principales: Wang, Chenyu, Barnett, Michael H., Yiannikas, Con, Barton, Joshua, Parratt, John, You, Yuyi, Graham, Stuart L., Klistorner, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705629/
https://www.ncbi.nlm.nih.gov/pubmed/31454773
http://dx.doi.org/10.1212/NXI.0000000000000593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705629/
https://www.ncbi.nlm.nih.gov/pubmed/31454773
http://dx.doi.org/10.1212/NXI.0000000000000593

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