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Lesion activity and chronic demyelination are the major determinants of brain atrophy in MS

OBJECTIVE: To evaluate the combined effect of lesion activity and pathologic processes occurring in both chronically demyelinated lesions and normal-appearing white matter (NAWM) on brain atrophy in MS. METHODS: Pre- and post-gadolinium T1, fluid attenuation inversion recovery, and diffusion tensor...

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Detalles Bibliográficos
Autores principales:	Wang, Chenyu, Barnett, Michael H., Yiannikas, Con, Barton, Joshua, Parratt, John, You, Yuyi, Graham, Stuart L., Klistorner, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705629/ https://www.ncbi.nlm.nih.gov/pubmed/31454773 http://dx.doi.org/10.1212/NXI.0000000000000593

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