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System analysis of cross-talk between nuclear receptors reveals an opposite regulation of the cell cycle by LXR and FXR in human HepaRG liver cells

Transcriptional regulations exert a critical control of metabolic homeostasis. In particular, the nuclear receptors (NRs) are involved in regulating numerous pathways of the intermediate metabolism. The purpose of the present study was to explore in liver cells the interconnectedness between three o...

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Detalles Bibliográficos
Autores principales: Wigger, Leonore, Casals-Casas, Cristina, Baruchet, Michaël, Trang, Khanh B., Pradervand, Sylvain, Naldi, Aurélien, Desvergne, Béatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705839/
https://www.ncbi.nlm.nih.gov/pubmed/31437187
http://dx.doi.org/10.1371/journal.pone.0220894