Participation of PLK1 and FOXM1 in the hyperplastic proliferation of pulmonary artery smooth muscle cells in pulmonary arterial hypertension

Vascular smooth muscle cells from the pulmonary arteries (HPASMC) of subjects with pulmonary arterial hypertension (PAH) exhibit hyperplastic growth. The PAH HPASMC display an increased sensitivity to fetal bovine serum (FBS) and undergo growth at a very low, 0.2%, FBS concentration. On the other ha...

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Detalles Bibliográficos
Autores principales: Wilson, Jamie L., Wang, Lizhen, Zhang, Zeyu, Hill, Nicholas S., Polgar, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705859/
https://www.ncbi.nlm.nih.gov/pubmed/31437238
http://dx.doi.org/10.1371/journal.pone.0221728

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