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Antinociceptive effect of PnTx4(5-5), a peptide from Phoneutria nigriventer spider venom, in rat models and the involvement of glutamatergic system

BACKGROUND: The venom of Phoneutria nigriventer spider is a source of numerous bioactive substances, including some toxins active in insects. An example is PnTx4(5-5) that shows a high insecticidal activity and no apparent toxicity to mice, although it inhibited NMDA-evoked currents in rat hippocamp...

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Detalles Bibliográficos
Autores principales:	Oliveira, Camila Franco Batista, Alves, Daniela Pereira, Emerich, Bruna Luiza, de Figueiredo, Suely Gomes, Cordeiro, Marta do Nascimento, Borges, Márcia Helena, Richardson, Michael, Pimenta, Adriano Monteiro de Castro, Duarte, Igor Dimitri Gama, de Lima, Maria Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Centro de Estudos de Venenos e Animais Peçonhentos 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706083/ https://www.ncbi.nlm.nih.gov/pubmed/31467512 http://dx.doi.org/10.1590/1678-9199-JVATITD-2019-0022

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