Cargando…
Association between disorganization of retinal inner layers and visual acuity after proliferative diabetic retinopathy surgery
We report to evaluate if disorganization of the retinal inner layers (DRIL) obtained by swept-source optical coherence tomography (SS-OCT) predicts the postoperative best-corrected visual acuity (BCVA) to treat proliferative diabetic retinopathy (PDR). Twenty-one eyes of 21 patients who underwent vi...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706380/ https://www.ncbi.nlm.nih.gov/pubmed/31439887 http://dx.doi.org/10.1038/s41598-019-48679-z |
_version_ | 1783445688793694208 |
---|---|
author | Ishibashi, Tomoyuki Sakimoto, Susumu Shiraki, Nobuhiko Nishida, Kentaro Sakaguchi, Hirokazu Nishida, Kohji |
author_facet | Ishibashi, Tomoyuki Sakimoto, Susumu Shiraki, Nobuhiko Nishida, Kentaro Sakaguchi, Hirokazu Nishida, Kohji |
author_sort | Ishibashi, Tomoyuki |
collection | PubMed |
description | We report to evaluate if disorganization of the retinal inner layers (DRIL) obtained by swept-source optical coherence tomography (SS-OCT) predicts the postoperative best-corrected visual acuity (BCVA) to treat proliferative diabetic retinopathy (PDR). Twenty-one eyes of 21 patients who underwent vitrectomy for PDR were studied retrospectively. BCVA and SS-OCT images were obtained until 6 months postoperatively. The associations between BCVA and SS-OCT parameters measured in a 1-mm central foveal area were evaluated. The DRIL length, external limiting membrane disruption, and ellipsoid zone (EZ) disruption 1 month postoperatively were associated positively with the postoperative logarithm of the minimum angle of resolution (logMAR) BCVA at 1, 3, and 6 months (1 month, p = 0.009, p = 0.013, p = 0.001; 3 months, p = 0.03, p = 0.021, p = 0.002; and 6 months, p = 0.021, p = 0.013, and p = 0.005, respectively). The eyes with a 500-µm or longer DRIL 1 month postoperatively (19%, 4/21 eyes) had significantly worse VA at 1, 3, and 6 months postoperatively (p = 0.007, p = 0.008, and p = 0.020, respectively). Multilinear regression analysis of all visits until 6 months postoperatively showed that the DRIL was correlated more significantly (p = 0.0004) with logMAR BCVA than the disrupted EZ length. The DRIL in the early postoperative period may predict the visual outcomes after treating PDR. |
format | Online Article Text |
id | pubmed-6706380 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-67063802019-09-08 Association between disorganization of retinal inner layers and visual acuity after proliferative diabetic retinopathy surgery Ishibashi, Tomoyuki Sakimoto, Susumu Shiraki, Nobuhiko Nishida, Kentaro Sakaguchi, Hirokazu Nishida, Kohji Sci Rep Article We report to evaluate if disorganization of the retinal inner layers (DRIL) obtained by swept-source optical coherence tomography (SS-OCT) predicts the postoperative best-corrected visual acuity (BCVA) to treat proliferative diabetic retinopathy (PDR). Twenty-one eyes of 21 patients who underwent vitrectomy for PDR were studied retrospectively. BCVA and SS-OCT images were obtained until 6 months postoperatively. The associations between BCVA and SS-OCT parameters measured in a 1-mm central foveal area were evaluated. The DRIL length, external limiting membrane disruption, and ellipsoid zone (EZ) disruption 1 month postoperatively were associated positively with the postoperative logarithm of the minimum angle of resolution (logMAR) BCVA at 1, 3, and 6 months (1 month, p = 0.009, p = 0.013, p = 0.001; 3 months, p = 0.03, p = 0.021, p = 0.002; and 6 months, p = 0.021, p = 0.013, and p = 0.005, respectively). The eyes with a 500-µm or longer DRIL 1 month postoperatively (19%, 4/21 eyes) had significantly worse VA at 1, 3, and 6 months postoperatively (p = 0.007, p = 0.008, and p = 0.020, respectively). Multilinear regression analysis of all visits until 6 months postoperatively showed that the DRIL was correlated more significantly (p = 0.0004) with logMAR BCVA than the disrupted EZ length. The DRIL in the early postoperative period may predict the visual outcomes after treating PDR. Nature Publishing Group UK 2019-08-22 /pmc/articles/PMC6706380/ /pubmed/31439887 http://dx.doi.org/10.1038/s41598-019-48679-z Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Ishibashi, Tomoyuki Sakimoto, Susumu Shiraki, Nobuhiko Nishida, Kentaro Sakaguchi, Hirokazu Nishida, Kohji Association between disorganization of retinal inner layers and visual acuity after proliferative diabetic retinopathy surgery |
title | Association between disorganization of retinal inner layers and visual acuity after proliferative diabetic retinopathy surgery |
title_full | Association between disorganization of retinal inner layers and visual acuity after proliferative diabetic retinopathy surgery |
title_fullStr | Association between disorganization of retinal inner layers and visual acuity after proliferative diabetic retinopathy surgery |
title_full_unstemmed | Association between disorganization of retinal inner layers and visual acuity after proliferative diabetic retinopathy surgery |
title_short | Association between disorganization of retinal inner layers and visual acuity after proliferative diabetic retinopathy surgery |
title_sort | association between disorganization of retinal inner layers and visual acuity after proliferative diabetic retinopathy surgery |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706380/ https://www.ncbi.nlm.nih.gov/pubmed/31439887 http://dx.doi.org/10.1038/s41598-019-48679-z |
work_keys_str_mv | AT ishibashitomoyuki associationbetweendisorganizationofretinalinnerlayersandvisualacuityafterproliferativediabeticretinopathysurgery AT sakimotosusumu associationbetweendisorganizationofretinalinnerlayersandvisualacuityafterproliferativediabeticretinopathysurgery AT shirakinobuhiko associationbetweendisorganizationofretinalinnerlayersandvisualacuityafterproliferativediabeticretinopathysurgery AT nishidakentaro associationbetweendisorganizationofretinalinnerlayersandvisualacuityafterproliferativediabeticretinopathysurgery AT sakaguchihirokazu associationbetweendisorganizationofretinalinnerlayersandvisualacuityafterproliferativediabeticretinopathysurgery AT nishidakohji associationbetweendisorganizationofretinalinnerlayersandvisualacuityafterproliferativediabeticretinopathysurgery |