The Eleanor ncRNAs activate the topological domain of the ESR1 locus to balance against apoptosis

MCF7 cells acquire estrogen-independent proliferation after long-term estrogen deprivation (LTED), which recapitulates endocrine therapy resistance. LTED cells can become primed for apoptosis, but the underlying mechanism is largely unknown. We previously reported that Eleanor non-coding RNAs (ncRNA...

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Detalles Bibliográficos
Autores principales: Abdalla, Mohamed Osama Ali, Yamamoto, Tatsuro, Maehara, Kazumitsu, Nogami, Jumpei, Ohkawa, Yasuyuki, Miura, Hisashi, Poonperm, Rawin, Hiratani, Ichiro, Nakayama, Hideki, Nakao, Mitsuyoshi, Saitoh, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706407/
https://www.ncbi.nlm.nih.gov/pubmed/31439835
http://dx.doi.org/10.1038/s41467-019-11378-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706407/
https://www.ncbi.nlm.nih.gov/pubmed/31439835
http://dx.doi.org/10.1038/s41467-019-11378-4

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